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Week 10 NFL Season

Week 10 NFL Sunday Games Preview

Posted on November 7, 2025December 22, 2025 by bettherent
Week 10 of the 2025 NFL season

November 9, 2025


INTERNATIONAL GAME (9:30 AM ET)

Atlanta Falcons (3-5) at Indianapolis Colts (7-2)

Olympic Stadium Berlin | NFL Network

This marks the NFL’s first regular-season game in Berlin. The Colts lead the NFL in scoring offense (32.2 PPG) behind QB Daniel Jones (2,404 pass yards) and RB Jonathan Taylor, who leads the league in scrimmage TDs (14) and rush TDs (12) with 1,113 scrimmage yards.

Atlanta’s Bijan Robinson ranks third in the NFL with 1,058 scrimmage yards. This marks the first game since 2002 to feature opposing players each with at least 1,000 scrimmage yards by Week 10. Rookie QB Michael Penix Jr. is finding his stride after throwing three TDs with zero interceptions in Week 9.

Key Matchup: A battle of elite running backs—Colts RB Jonathan Taylor (1,113 scrimmage yards, 14 TDs) versus Falcons RB Bijan Robinson (1,058 scrimmage yards).


EARLY WINDOW (1:00 PM ET)

New Orleans Saints (1-8) at Carolina Panthers (5-4)

Bank of America Stadium | FOX

The Saints’ season continues to unravel as they limp into Carolina with just one win. Rookie QB Tyler Shough made his first career start in Week 9, while Alvin Kamara needs just 88 receiving yards to become the sixth player ever with 5,000+ rushing and 5,000+ receiving yards.

Carolina’s Rico Dowdle is having a breakout season, leading the NFL with 103 carries and 652 rush yards since Week 5. He rushed for 130 yards and two touchdowns last week. QB Bryce Young is finding his rhythm at home with solid performances in two of three home games this season.

Key Matchup: Saints RB Alvin Kamara (1,261 career scrimmage yards vs. CAR) against Carolina’s improved defense led by S Tre’von Moehrig, who won NFC Defensive Player of the Week with an INT and two TFLs last week.


New York Giants (2-7) at Chicago Bears (5-3)

Soldier Field | FOX

The Giants are struggling with rookie QB Jaxson Dart under center, though he’s become the first rookie QB in NFL history with a TD pass and rush TD in four straight games. LB Brian Burns leads the NFL with 11 sacks and has recorded a sack in eight of the team’s first nine games.

Chicago’s offense exploded for 47 points last week behind QB Caleb Williams’ historic performance (280 pass yards, 53 rush yards, 22 receiving yards). Rookie TE Colston Loveland had a breakout game with 118 yards and two TDs, including the 58-yard game-winner with 17 seconds left. The Bears lead the NFL in takeaways (19) and turnover differential (+13).

Key Matchup: Giants LB Brian Burns (11 sacks) versus Bears’ offensive line protecting the versatile Caleb Williams.


Jacksonville Jaguars (5-3) at Houston Texans (3-5)

NRG Stadium | CBS

Jacksonville QB Trevor Lawrence is coming off a two-rush-TD performance and faces a Houston defense that’s allowed 18 points per game. RB Travis Etienne has 50+ scrimmage yards in all eight games this season and aims for his 11th consecutive game with 50+ scrimmage yards.

Houston’s C.J. Stroud has been solid at home with TD passes and 95+ ratings in three of his past four home games. WR Nico Collins leads the team with 414 receiving yards despite missing time. The Texans rank second in the NFL in rushing yards allowed (267.4 per game).

Key Matchup: Jaguars LB Devin Lloyd (four INTs this season) against Texans QB C.J. Stroud, who has five career games versus Jacksonville with 200+ yards and TD passes.


Buffalo Bills (6-2) at Miami Dolphins (2-7)

Hard Rock Stadium | CBS

Josh Allen and the Bills are rolling with six wins in their last seven games. Allen made history last week, surpassing Cam Newton with the most rushing TDs by a QB in NFL history (including playoffs) with 79. He’s dominated Miami with a 13-2 record, 45 total TDs, and a 110.3 passer rating in 15 career starts.

Miami’s Tua Tagovailoa has thrown 15 TDs but also 11 INTs this season. RB De’Von Achane leads the team with 880 scrimmage yards and ranks tied-first among RBs with four receiving TDs. The Dolphins desperately need a win to salvage their season.

Key Matchup: Bills RB James Cook (867 rush yards, only player with 100+ rush yards in five games) versus Miami’s struggling run defense.


Baltimore Ravens (3-5) at Minnesota Vikings (4-4)

U.S. Bank Stadium | FOX

Lamar Jackson is having a historic season with an NFL-record 136.7 passer rating through Week 9. He had four TD passes with zero interceptions last week. Jackson can surpass Ken Stabler for the fourth-most wins by a QB in their first 100 career starts with a victory. RB Derrick Henry (629 rush yards, six TDs) remains a force.

Minnesota’s rookie QB J.J. McCarthy became the first player in NFL history with 2+ TD passes and a rush TD in two of his first three career games. The Vikings’ defense recorded a season-high five sacks last week. WR Justin Jefferson leads the team with 649 receiving yards and aims for his seventh consecutive game with 5+ receptions.

Key Matchup: Ravens QB Lamar Jackson (136.7 passer rating) against Minnesota’s defense, which is tied for allowing 20-or-fewer points in seven games.


Cleveland Browns (2-6) at New York Jets (1-7)

MetLife Stadium | CBS

Cleveland DE Myles Garrett is having a monster season with 10 sacks in eight games, including a career-high five-sack performance in Week 8. The Browns’ defense will face a Jets offense that posted 502 yards last week.

The Jets’ Justin Fields is the only QB in the NFL with zero interceptions this season. RB Breece Hall threw a TD pass in addition to his two rushing TDs last week. The Jets recorded their first win of the season against Cincinnati and are desperate for momentum.

Key Matchup: Browns DE Myles Garrett (10 sacks, has sack and TFL in all six career games vs. NYJ) versus Jets QB Justin Fields (zero INTs this season).


New England Patriots (7-2) at Tampa Bay Buccaneers (6-2)

Raymond James Stadium | CBS

This matchup features teams tied for the best records in their respective conferences. Patriots rookie QB Drake Maye is the fourth player in NFL history with 200+ passing yards and a 100+ passer rating in eight consecutive games. He ranks second in passer rating (116.9) and tied-third in TD passes (17).

Tampa Bay QB Baker Mayfield has the Bucs at 6-2 with 13 TD passes and just two interceptions. S Antoine Winfield Jr. had an INT and fumble recovery last week. The Buccaneers’ defense has been opportunistic all season.

Key Matchup: Patriots QB Drake Maye’s hot streak versus Tampa Bay’s defense featuring S Antoine Winfield Jr. and a secondary ranking fourth in yards allowed (321.4 per game).


LATE AFTERNOON WINDOW (4:05/4:25 PM ET)

Arizona Cardinals (3-5) at Seattle Seahawks (6-2)

Lumen Field | CBS | 4:05 PM ET

Arizona QB Kyler Murray and Jacoby Brissett have been splitting time, with Brissett coming off a three-TD performance. TE Trey McBride became the third TE ever with 5+ receptions in 10 straight games and has 52 catches for 476 yards and five TDs this season.

Seattle’s Jaxon Smith-Njigba leads the NFL with 948 receiving yards and six 100-yard games. He’s had 8+ catches and 100+ yards in four consecutive games and can make history with a fifth. QB Sam Darnold leads the NFC with a 116.0 passer rating and has thrown 16 TDs with five INTs.

Key Matchup: Cardinals TE Trey McBride (on historic reception streak) versus Seattle’s defense that ranks second in scoring defense (18.8 PPG).


Los Angeles Rams (6-2) at San Francisco 49ers (6-3)

Levi’s Stadium | FOX | 4:25 PM ET

This NFC West showdown features two of the conference’s hottest offenses. Rams QB Matthew Stafford leads the NFL with 21 TD passes and needs just two more to reach 400 career regular-season TDs. WR Davante Adams leads the league with eight TD receptions and has 111 career TD catches, tied for eighth all-time.

San Francisco’s Christian McCaffrey continues his dominance with an NFL-leading 1,222 scrimmage yards. He had 173 scrimmage yards and two TDs last week in his 16th career game with both a rushing and receiving TD—most in NFL history. The 49ers won the Week 5 meeting 26-23 in overtime.

Key Matchup: Rams WR Davante Adams (eight TDs this season) versus 49ers’ secondary led by CB Renardo Green (seven PDs).


Detroit Lions (5-3) at Washington Commanders (3-6)

Northwest Stadium | FOX | 4:25 PM ET

Detroit QB Jared Goff ranks tied-third in TD passes (17) and fourth in passer rating (115.2). RB Jahmyr Gibbs had 175 scrimmage yards in the playoff meeting last January. WR Amon-Ra St. Brown needs 11 receptions to reach 500 for his career and has seven TD catches this season.

Washington’s Marcus Mariota has thrown a TD pass in every start this season. Rookie RB Jacory Croskey-Merritt ranks third among rookies with 440 rush yards. CB Mike Sainristil is tied for fourth in the NFL with three interceptions. The Lions won the playoff meeting 45-31 last season.

Key Matchup: Lions WR Amon-Ra St. Brown (635 yards, seven TDs) against Commanders CB Mike Sainristil (three INTs, tied-fourth in NFL).

All times Eastern. Game information and player statistics current through Week 9.


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