Sunday Afternoon Slate: 3 games from Week 5 of the 2026 NFL season, Sunday, October 11, 2026. Each game below carries its captured line, the statistic on which the two teams differ most in league rank, their recent head-to-head record, and the conditions and availability picture as it stands.
The Slate
| Matchup | Kickoff | Spread | Total | Venue |
|---|---|---|---|---|
| Denver Broncos at Los Angeles Chargers | 4:05 PM EDT | Broncos -3.5 | 41.5 | SoFi Stadium |
| Detroit Lions at Arizona Cardinals | 4:25 PM EDT | Lions -5.5 | 54.5 | State Farm Stadium |
| San Francisco 49ers at Seattle Seahawks | 4:25 PM EDT | Seahawks -3 | 45.5 | Lumen Field |
Game by Game
Denver Broncos at Los Angeles Chargers
Broncos -3.5, Chargers +3.5, total 41.5, moneyline Broncos -192, Chargers +160 (DraftKings; captured Oct 10, 2026 at 7:00 PM EDT).
Sacks allowed: Broncos 2nd (5), Chargers 26th (12).
Broncos 6-4 in their last 10, scoring 20.7 and allowing 21.0; Chargers 3-7 in their last 10, scoring 16.1 and allowing 21.0.
Broncos are 5-5 in the last 10 meetings; 5-5 against the spread; 4 over, 6 under.
Indoors, so conditions are not a factor.
Broncos: 23 on the practice report (6 did not practice, 2 limited); Chargers: 63 on the practice report (21 did not practice, 13 limited).
Detroit Lions at Arizona Cardinals
Lions -5.5, Cardinals +5.5, total 54.5, moneyline Lions -258, Cardinals +210 (DraftKings; captured Oct 10, 2026 at 7:00 PM EDT).
Interceptions thrown: Lions 1st (0), Cardinals 23rd (4).
Lions 4-6 in their last 10, scoring 27.4 and allowing 29.7; Cardinals 1-9 in their last 10, scoring 19.4 and allowing 32.2.
Lions are 5-4-1 in the last 10 meetings; 5-5 against the spread; 4 over, 6 under.
Clear, 83°F, wind 25 mph, 17% chance of precipitation.
Lions: 30 on the practice report (7 did not practice, 6 limited); Cardinals: 46 on the practice report (6 did not practice, 14 limited).
San Francisco 49ers at Seattle Seahawks
49ers +3, Seahawks -3, total 45.5, moneyline 49ers +136, Seahawks -162 (DraftKings; captured Oct 10, 2026 at 7:00 PM EDT).
Tackles for loss: 49ers 31st (10), Seahawks 1st (28).
49ers 8-2 in their last 10, scoring 28.1 and allowing 22.6; Seahawks 9-1 in their last 10, scoring 28.4 and allowing 16.9.
49ers are 7-3 in the last 10 meetings; 6-4 against the spread; 4 over, 6 under.
Clear, 59°F, wind 9 mph, 0% chance of precipitation.
49ers: 55 on the practice report (15 did not practice, 13 limited); Seahawks: 51 on the practice report (9 did not practice, 12 limited).
Team statistics – 2026 Season – Through Week 5. League ranks are out of 32, and 1 is best on every row — fewest penalties and fewest interceptions thrown rank first, not most. The statistic shown for each game is the one on which the two teams differ most in league rank; ties are broken by a fixed field order, so the choice is the same on every run. Practice-report counts are practice participation levels, not game-status designations: no Out, Doubtful or Questionable designations have been published for these games yet.